Extracellular signal-regulated kinases (ERKs)

Definition:

Extracellular signal-regulated kinases (ERKs)are members of the mitogen-activated protein kinase superfamily, identified as molecules activated in neurons by the exposure of peripheral tissues to noxious stimuli.Extracellular signal-regulated kinases (ERKs) are involved in functions ofpromoting cell proliferation.

References:

[1]. Kondo M, et al. Extracellular signal-regulated kinases (ERK) 1 and 2 as a key molecule in pain research. J Oral Sci. 2020;62(2):147-149. [Content Brief]

[2]. Wei F, et al. Extracellular signal-regulated kinases modulate DNA damage response - a contributing factor to using MEK inhibitors in cancer therapy. Curr Med Chem. 2011;18(35):5476-82. [Content Brief]

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